8-MOP methoxsalen

Brand name


Generic name


Side effects of 8-MOP

  • nausea
  • trouble sleeping (insomnia)
  • depression
  • nervousness
  • sleep problems (insomnia)
  • cold sores
  • headache
  • dizziness
  • leg pain
  • mild skin changes (itching, drying, redness, tenderness, or darkening of skin) when this drug is used along with UVA light treatment

Warning for 8-MOP

Methoxsalen with UV radiation should be used only by physicians who have special competence in the diagnosis and treatment of psoriasis and vitiligo and who have special training and experience in photo chemotherapy. Psoralen and ultraviolet radiation therapy should be under constant supervision of such a physician. For the treatment of patients with psoriasis, photo chemotherapy should be restricted to patients with severe, recalcitrant, disabling psoriasis which is not adequately responsive to other forms of therapy, and only when the diagnosis is certain. Because of the possibilities of ocular damage, aging of the skin, and skin cancer (including melanoma), the patient should be fully informed by the physician of the risks inherent in this therapy. When methoxsalen is used in combination with photopheresis, refer to the UVAR* System Operator's Manual for specific warnings, cautions, indications, and instructions related to photopheresis.

CAUTION: 8-MOP® Capsules (Methoxsalen Hard Gelatin Capsules) may not be interchanged with Oxsoralen-Ultra®Capsules (Methoxsalen Soft Gelatin Capsules) without retitration of the patient.

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